肿块最长径、边缘及淋巴结皮质厚度、形态分型、血供类型是腋窝淋巴结转移的独立危险因素。建模组总分值曲线下面积(area under curve,AUC)为0.783,验证组AUC为0.831,分值分段转移率符合预设。
结论:
超声评估分类法在预测乳腺癌腋窝淋巴结转移方面具有可靠性。
Abstract
Objective:
To explore the feasibility of ultrasound classification assessment method to predict axillary lymph node metastasis in breast cancer.
Methods:
A total of 1 235 breast cancer patients admitted to The First Affiliated Hospital of Nanjing Medical University were selected and divided into a modeling group (800 cases) and a validation group (435 cases) according to the order of examination time. The statistically significant independent risk factors were screened and assigned by statistical analysis
and the total score was segmented to create a classification evaluation system. The receiver
operating characteristic (ROC) curve of the total score of the modeling group was drawn to evaluate the diagnostic efficiency of the system
and then the verification group was substituted to verify the performance of the system.
Results:
After statistical testing
the longest diameter and margins of the mass
as well as the thickness of the lymph node cortex
morphological typology
and type of blood supply were independent risk factors for axillary lymph node metastasis. The area under curve (AUC) evaluated by the modeling group was 0.783. The AUC evaluated by the verification group was 0.831
and the probability of malignancy was consistent with the assumption.
Conclusion:
The new assessment classification system of conventional ultrasound is reliable in predicting breast cancer axillary lymph node metastasis.