Objective:

To investigate the application value of ultrasonography features combined with inflammatory markers in bladder urothelial carcinoma (BUC) grading.

Methods:

The ultrasound features of 95 patients with BUC dia

gnosed by pathological findings in Lanzhou University Second Hospital from March 2021 to September 2022 were retrospectively analyzed. According to the pathological results

the patients were divided into high-grade group (

n

=65) and low-grade group (

n

=30)

and the general data

ultrasound characteristics and inflammatory markers were compared between the two groups. Receiver operating characteristic (ROC) curves were plotted to evaluate the diagnostic efficacy of ultrasound characteristics combined with inflammatory markers for low-grade and high-grade BUC.

Results:

There were significant differences in age (

t

=0.570

P

=0.001)

transverse diameter (

t

=-4.158

P

=0.000)

longitudinal diameter (

t

=-3.932

P

=0.000)

blood flow grade (

2

=10.454

P

=0.005) and NLR (

Z

=-2.210

P

=0.027) between the two groups (

P

＜0.05). Logistic regression analysis showed that age (OR=3.360

P

=0.024) and neutrophil to lymphocyte ratio (NLR) (OR=3.303

P

=0.029) were independent risk factors for high-grade BUC. The area under the ROC curve

sensitivity

and specificity of ultrasound features combined with inflammatory markers in differentiating high-grade BUC were 0.823

81.5%

73.3%.

Conclusion:

Ultrasonography characteristics combined with inflammatory markers has certain value in the BUC grading.