Objective:

To analyze the ultrasonographic features of hepatic epithelioid hemangioendothelioma (HEHE) and to improve the accuracy of preoperative ultrasonography.

Methods:

A retrospective analysis was performed on the routine ultrasound findings and contrast-enhanced ultrasound (CEUS) characteristics of 9 HEHE patients diagnosed by pathological examination

and the relevant literatures were reviewed.

Results:

The tumors in 9 patients with HEHE were all multiple mass-occupying

located under the liver capsule (partially convex) or close to the intrahepat

ic blood vessels (lollipop-like). All the tumors had regular morphology and uneven internal echo

1 case was hyper-echoic with acoustic halo

and the rest were hypo-echoic. Two cases had unclear borders and 7 cases had clear borders. CEUS features: annular hyperenhancement in arterial phase

low enhancement with portal venous phase and delayed phase. The central part was not continuously enhanced

and the enhancement mode was characterized by fast-in and fast-out. The pathological diagnosis was HEHE.

Conclusion:

Preoperative ultrasound diagnosis of HEHE is difficult. In clinical work

liver tumors are distributed under the liver capsule or close to the intrahepatic blood vessels (lollipop-like). The lesions with characteristics of enhanced around the periphery and fast-forward without central enhancement after CEUS

HEHE should be taken into account.