Objective:

To investigate the value of color Doppler ultrasound Finkler scoring system combined with serum tumor markers in the differential diagnosis of benign and malignant ovarian tumors in children.

Methods:

A total of 137 children with ovarian tumor confirmed by operation in Children’s Hospital of Fudan University were selected

including 32 cases of malignant ovarian tumor (malignant group) and 105 cases

of benign ovarian tumor (benign group). Ultrasonic characteristics

Finkler score of color Doppler ultrasound

alpha-fetoprotein (AFP) and neuron-specific enolase (NSE) levels of the two groups were compared. The diagnostic efficacies of color Doppler Finkler score

AFP and NSE alone and in combination for malignant ovarian tumors in children were analyzed.

Results:

There were significant differences in morphology

echo

blood flow signal

Finkler score of color Doppler ultrasound

AFP and NSE levels between the two groups (

P

＜0.05). The efficacy of Finkler score of color Doppler ultrasound combined with AFP and NSE in the identification of benign and malignant ovarian tumors in children was higher than those detected by ultrasonography alone or serological indexes

and the differences were statistically significant (

P

＜0.05).

Conclusion:

Color Doppler ultrasound Finkler score combined with serum tumor markers AFP and NSE can significantly improve the value of differential diagnosis of benign and malignant ovarian tumors in children.