Objective:

To anal

yze the diagnostic value of ultrasound-assisted mammography in dense breast screening.

Methods:

A retrospective analysis of 1 096 patients with dense breast masses

who underwent both conventional ultrasound and mammography in Shanghai General Hospital

Shanghai Jiao Tong University School of Medicine from January 2013 to August 2019. According to age

tumor size and with or without calcification

the patients were divided into several groups. Taking the pathological results as the gold standard

the influence of combined examination on the classification of Breast Imaging Reporting and Data System (BI-RADS) versus mammography was discussed. At the same time

area under curve (AUC)

malignant detection rate

sensitivity

and specificity of mammography alone and mammography combined with conventional ultrasound in the diagnosis of dense breast masses were obtained and compared.

Results:

The increased rate of breast cancer in BI-RADS 0 and 1-3 categories by combined examination were 14.8% and 15.1%

respectively. The AUCs of mammography and mammography combined with conventional ultrasound in the diagnosis of dense breast mass were 0.774 and 0.937 (

Z

=13.757

P

＜0.001)

respectively. Regardless of the dense breast masses with different age groups

different size groups and groups with or without calcification

AUC of mammography combined withconventional ultrasound was significantly higher than that of mammography alone

and the differences were statistically significant (

P

＜0.05). The sensitivity of mammography alone and mammography combined with conventional ultrasound were 65.6% and 93.3% (

χ

2

= 54.955

P

＜0.001); the specificity were 89.3% and 94.1% (

χ

2

=353.013

P

＜0.001); the detection rate of breast cancer increased from 24.3% (266/1 096) to 34.6% (379/1 096

χ

2

= 293.450

P

＜0.001). In different age groups

different size groups and groups with or without calcificat

ion

the sensitivity and specificity of mammography combined with conventional ultrasound in the diagnosis of dense breast mass were significantly higher than mammography

with statistical significance (

P

＜0.05).

Conclusion:

Compared with mammography alone

ultrasound-assisted mammography can improve the detection rate of malignant tumors in patients with dense mammary glands. In particular

ultrasound-assisted mammography is of great significance for breast cancer screening in people with dense breast

whose age over 55 years or whose mass diameter ＜2 cm.