Objective:

To assess the diagnostic accuracy of contrast-enhanced ultrasound (CEUS) in conjunction with 2D ultrasound (2DUS) in the diagnosis of the breast benign and malignant lesions

with pathological histological analysis serving as the gold standard.

Methods:

A total of 1 299 female breast lesions patients who underwent breast 2DUS and CEUS in Tenth People’s Hospital of Tongji University from February 2018 to August 2023

with pathological histological examinat

ion were included in this study

and patients underwent examination with 2DUS Breast Imaging Reporting and Data System (BI-RADS) and CEUS combined with 2DUS

and were compared and analyzed for the CEUS features of breast benign and malignant lesions as well as the sensitivity

specificity

accuracy

positive predictive value

and negative predictive value under the two examination modalities.

Results:

Based on the findings from pathological histological examinations

the 1 299 patients were distributed into two groups

with 807 cases falling under the benign lesion group and 492 cases classified as malignant lesions group. 2DUS BI- RADS and CEUS combined with 2DUS examination were performed respectively

the sensitivity (96.1%) and accuracy rate (88.8%) of CEUS combined with 2DUS examination was significantly higher than the 2DUS BI-RADS examination

which suggested that the diagnostic value of CEUS combined with 2DUS was higher

and it also had a high sensitivity (95.9%) for the detection of benign and malignant 4 types of BI-RADS lesions.

Conclusion:

CEUS combined with 2DUS can be used together in the differential diagnosis of breast benign and malignant lesions

and the combined detection of the two has a high diagnostic value and can improve the diagnostic accuracy.