Objective:

To explore the value of Gynecology Imaging Reporting and Data System (GI-RADS) grading and tumor markers in the differentiation of benign and malignant ovarian tumors in children.

Methods:

The ultrasonographic examination and the detection results of cancer antigen (CA) 125 and CA19-9 in 100 cases of ovarian tumo

rs in children were retrospectively analyzed. The level of benign and malignant tumor markers and the ultrasonographic features were compared. At the same time

the efficacy of various diagnostic methods was analyzed by receiver operating characteristic (ROC) curve.

Results:

CA19-9 and CA125 in malignant group were higher than those in benign group ［(81.61±9.14) kU/L

vs

(19.55±4.85) kU/L

t

=34.552; (68.42± 6.15) kU/L

vs

(25.71±5.31) kU/L

t

=23.747;

P

＜0.05］. The diagnostic accuracy of GI-RADS grading

CA19-9

CA125

and combined diagnosis was 86.00%

76.00%

72.00%

97.00%. At the same time

by ROC curve analysis

the area under curve (AUC) of GI-RADS grading

CA19-9

CA125

and combined diagnosis in differential diagnosis of benign and malignant ovarian tumors were 0.833

0.689

0.667

and 0.939

respectively.

Conclusion:

Combining GI-RADS grading and tumor markers can improve the diagnostic accuracy in differentiating benign and malignant ovarian tumors.