对44例直肠腺癌患者行磁共振成像(magnetic resonance imaging,MRI)扫描,采用3种不同感兴趣区(region of interest,ROI)选取方法测量肿块ADC值。方法Ⅰ:选择增强序列强化最明显的部位作为ROI,在ADC图相应区域勾勒强化区范围并测量ADC值。方法Ⅱ:选择指数表观扩散系数(exponential apparent diffusion coefficient,eADC)图上直肠癌病灶内信号最明亮部位,沿其边缘勾勒,测量ADC值。方法Ⅲ:在ADC图上选择肿块最大层面,并沿病灶边缘勾勒病灶范围,测量ADC值。对比分析ADC值与病理学分化程度的相关性。
结果:
方法Ⅰ所得数据与病理学检查结果有相关性(
r
=0.718,
P
=0.000);方法Ⅱ所得数据与病理学检查结果有相关性(
r
=0.637,
P
=0.000);方法Ⅲ所得数据与病理学检查结果有相关性(
r
=0.643,
P
=0.000)。
结论:
方法Ⅰ测量所得ADC值与直肠癌病理学分化程度的相关性最好。
Abstract
Objective:
To investigate the correlation between apparent diffusion coefficient (ADC) measured by three methods and pathological results in rectal adenocarcinoma.
Methods:
A total of 44 rectal adenocarcinoma patients who underwent MRI before operation were retrospectively reviewed. Three methods were used to select the region of interest (ROI). MethodⅠ: the
most significantly enhanced region of lesions in the enhancement images was chosen as ROI. MethodⅡ: the brightest signal region of lesions in exponential apparent diffusion coefficient (eADC) image was chosen as ROI. MethodⅢ: the lesions largest area in ADC map was chosen as ROI. The correlation between ADC values measured by three methods and pathological results was compared.
Results:
The correlation r values between ADC values measured by three methods and pathological results were
r
1=0.718 (
P
=0.000)
r
2=0.637 (
P
=0.000) and
r
3=0.643 (
P
=0.000)
respectively.
Conclusion:
The correlation between ADC value measured by method Ⅰ and pathological results is the best.