Imaging research progress on fertility-preserving treatment for cervical cancer patients

WEN Xinran; Ai Hua; JIANG Xiran

doi:10.19732/j.cnki.2096-6210.2026.01.012

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Imaging research progress on fertility-preserving treatment for cervical cancer patients

Review | 更新时间：2026-03-25

- Imaging research progress on fertility-preserving treatment for cervical cancer patients
- Oncoradiology Vol. 35, Issue 1, Pages: 95-102(2026)
- 作者机构：
  
  1.中国医科大学第二临床学院医学影像技术系，辽宁沈阳 110004
  2.中国医科大学智能医学院生物医学工程系，辽宁沈阳 110122
- 作者简介：
  
  JIANG Xiran　E-mail: xxrjiang@cmu.edu.cn
- 基金信息：
  
  College Students’ Innovation and Entrepreneurship Training Program (Innovation Project) of China Medical University
- DOI：10.19732/j.cnki.2096-6210.2026.01.012
  CLC： R737.33;R445
- Received：10 October 2025，
  
  Published：28 February 2026
- 稿件说明：
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温欣然, 艾　华, 蒋西然. 宫颈癌患者保留生育功能治疗的影像学研究新进展［J］. 肿瘤影像学, 2026, 35(1): 95-102.

WEN X R, AI H, JIANG X RCitation:. Imaging research progress on fertility-preserving treatment for cervical cancer patients［J］. Oncoradiology, 2026, 35(1): 95-102.
温欣然, 艾　华, 蒋西然. 宫颈癌患者保留生育功能治疗的影像学研究新进展［J］. 肿瘤影像学, 2026, 35(1): 95-102. DOI： 10.19732/j.cnki.2096-6210.2026.01.012.

WEN X R, AI H, JIANG X RCitation:. Imaging research progress on fertility-preserving treatment for cervical cancer patients［J］. Oncoradiology, 2026, 35(1): 95-102. DOI： 10.19732/j.cnki.2096-6210.2026.01.012.

摘要

随着宫颈癌发病的年轻化趋势日益显著，保留患者生育功能的需求在临床治疗中不断增加。满足年轻患者的生育需求，不仅关乎疾病治疗本身，更涉及患者长期生活质量和心理健康。严格把握治疗适应证、进行精准的术前影像学评估与分期、合理选择治疗方式是保障治疗成功的关键。近年来，影像学技术在宫颈癌诊疗全流程中的作用日益凸显，影像学技术如超声、磁共振成像（magnetic resonance imaging，MRI）和正电子发射体层成像（positron emission tomography，PET）等在宫颈癌局部侵犯深度、肿瘤体积、宫旁浸润、淋巴结转移等方面的评估中各具优势。上述影像学及其衍生成像技术为宫颈癌患者保留生育功能治疗中的适应证筛选提供了客观依据，也为术式选择、疗效评估及随访中的复发监测提供了重要信息。本文系统综述宫颈癌患者保留生育功能治疗的现状与发展动态，重点讨论适应证的最新标准（如国际妇产科联盟分期、病理学类型、淋巴脉管间隙浸润、淋巴结转移等）、主要治疗方式（包括宫颈锥切术、宫颈切除术及经腹或经阴道宫颈切除术、淋巴结切除术等）的选择原则，详细阐述超声、MRI、PET等影像学方法在术前适应证评估及复发监测中的最新应用进展。文中特别聚焦于功能MRI及影像组学在宫颈癌患者保留生育功能方面的研究动态，旨在为临床医师选择合适的宫颈癌患者进行保留生育功能治疗提供依据，优化治疗决策。

Abstract

With the increasingly evident trend of younger onset in cervical cancer

the demand for preserving patients' reproductive function has grown significantly in clinical treatment. Meeting the fertility needs of young patients is not only crucial for disease management itself but also impacts their long-term quality of life and mental health. Strict adherence to treatment indications

precise preoperative imaging assessment and staging

and rational selection of treatment modalities are key to ensuring therapeutic success. In recent years

imaging technologies have played an increasingly prominent role throughout the entire cervical cancer diagnosis and treatment process. Techniques such as ultrasound

magnetic resonance imaging (MRI)

and positron emission tomography (PET) each offer distinct advantages in assessing factors like the depth of local invasion

tumor volume

parametrial involvement

and lymph node metastasis. These imaging modalities and their derivative techniques provide objective criteria for selecting candidates for fertility-preserving treatments in cervical cancer. They also offer crucial information for surgical decision-making

efficacy assessment

and monitoring recurrence during follow-up. This article systematically reviewed the current status and developments in fertility-preserving treatments for cervical cancer

focusing on the latest criteria for indications (such as International Federation of Gynecology and Obstetrics staging

histological type

lymphovascular space invasion

and lymph node metastasis)

selection principles for primary treatment modalities (including cervical conization

cervical resection

transabdominal or transvaginal cervical resection

and lymphadenectomy)

and details the latest applications of imaging methods such as ultrasound

MRI

and PET in preoperative indication assessment and recurrence monitoring. The article specifically focused on research developments in functional MRI and radiomics for fertility-preserving cervical cancer treatment. It aimed to provide evidence for clinicians to select suitable patients for fertility-preserving approaches

thereby optimizing treatment decisions.

关键词

Keywords

references

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